Special Interest Group (SIG) on EVs in Nervous System (EViNS)
Vision and Goal
EViNS aims to provide an efficient and inclusive framework to promote knowledge exchange on the biology, function, and potential clinical application of EVs in the nervous system, which is necessary to address key challenges and to develop research excellence at the interface of EV research and neuroscience.
The prospective goal of EViNS is to foster the collective development of productive activities such as working groups and to build partnerships with societies for neuroscience and related fields as well.
We promote diversity and young researchers.
 Chair Contact Info
Chair: Christian Neri (France) | Co-chairs: Eva-Maria Albers (Germany)| Tsuneya Ikezu (United States) | Andy Hill (Australia)
 Members
EViNS activities are supported by a core group of 21 leading experts in the field:
Shilpa Buch (USA), Luc Buée (France), Jason Howitt (Australia), Kendall Jensen (USA), Dimitrios Kapogiannis (USA), Efrat Levy (USA), Stephan Moma (Germany), Stefano Pluchino (UK), Juan Carlos Polanco (Australia), Julie Saugstad (USA), Randy Scheckman (USA), Anja Schneider (Germany), Jason Shepherd (USA), Mikael Simons (Germany), Rosmarin Vanderbrouke (Belgium), Guillaume Van Niel (France), Laura Vella (Australia), Claudia Verderio (Italy), David Walt (USA), Kenneth Witwer (USA), Yongjie Yang (USA)
Currently recruiting members:
If you are interested check the ISEV Special interest groups (SIGs) information page. To join, you must first be an ISEV member, and then you can login and complete the enrollment form.
 Ongoing activities (updated on 1st November 2024)
Working groups
Four Working Groups have been set during the 2024 general assembly of EViNS in Melbourne:
WG Brain-body communication/EVs and brain barriers
Leaders: Roosmarijn Vandenbroucke (Europe & Africa), Julien Saint-Pol (Europe & Africa), Jason Howitt (Asia Pacific)
WG EV-based biomarkers of neurodegenerative diseases
Leaders: Andy Hill (Asia Pacific), Julie Saugstad (Americas), Kendall Van Keuren-Jensen (Americas)
WG EVs and synaptic transmission
Leaders: Christian Neri (Europe & Africa), Jason Shepherd (Americas), Juan Carlos Polanco (Asia Pacific)
WG EV-mediated in vivo functions in CNS development, physiology & pathology, also covering Toolkit for EV research in the CNS
Leaders: Tsuneya Ikezu (Americas), Yongjie Yang (Americas)
Webinars
EViNS’ webinars are organized and facilitated by Tsuneya Ikezu (USA) & Stefano Pluchino (UK) in collaboration with the virtual EVClub series.
EViNS-EVClub sessions are scheduled for the following dates, generally at 12 noon EDT/ 6pm CET/ 12 midnight UTC+8:
Wednesday, November 20, 2024
Wednesday, January 15, 2025
Wednesday, March 19, 2025
Wednesday, May 21, 2025
Wednesday, July 16, 2025
Wednesday, September 17, 2025
Wednesday, November 19, 2025
Contact Tsuneya or Stefano if you would like to share an interesting study on EVs in nervous system.
Symposia and joint-sessions with neuroscience societies
Past activities
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ISEV’s 1st Symposium on EVs in Nervous Systems, Rome (Italy), December 2023, Rome (Italy),successfully brought together the community at large to discuss research progress and scientific challenges on several aspects of EV biogenesis, roles and applications (as biomarkers or therapeutics) in healthy or diseased nervous systems. During two and a half days, more than 200 participants from around the globe shared new data and prospective views, learnt from each other, and enjoyed networking in a high-profile conference (see the program).
This first-of-its-kind symposium was also the first meeting of the members of the ISEV Special Interest Group on EVs in Nervous System (SIG EViNS), which was supported by experts beyond the EV community and by leadership of the European Society for Neurochemistry & German Neuroscience Society. This added depth to discussions on how SIG EViNS can provide the most efficient and inclusive framework to promote knowledge exchange and discoveries on the biology, function, and potential clinical application of EVs in the nervous system.
The organization and success of the Symposium would not have been possible without the fantastic contribution of participants and help of EViNS core group members. The SIG EViNS met at ISEV2024 in Melbourne (Satellite meeting and General Assembly) and approved the development of the activities that are summarized below.
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