Rigor & Standardization Intersociety Working GroupsTo improve reproducibility, ISEV collaborates with other international societies. At present, there are three intersociety working groups, the ISEV-ELBS working group, the ISEV-ISAC-ISTH EV Flow cytometry working group, and the ISEV-ISCT working group. Whereas a Task force usually has ISEV members only, intersociety working groups have members from two or more international scientific organizations. ISEV-ELBS working groupHistoryThe ISEV-ELBS Intersociety Working Group was founded in 2023. ELBS is the European Liquid Biopsy Society, and this working group aims to improve the quality of biobanks used for clinical biomarker exploration, which includes EV-related biomarker research. In the last 20 years, there has been a revolution in early diagnosis, prognosis and therapeutic efficacy of diseases based on information collected from non-invasive liquid biopsies. Vision and aimsTogether the ISEV-ELBS Intersociety Working Group aims to foster collaboration between the two societies with the goal of promoting reproducibility of liquid biopsy-EV preparation and analysis and encouraging discussion on EV research and its applications in liquid biopsy approaches. Together the two societies will co-host meetings, develop collaborative initiatives and report developments in the EV-liquid biopsy field. This will foster the development of novel EV biomarkers and their translation to the clinic. Meet the ChairsCaterina Nardella Senior Scientist and Programme Manager, Laboratory of Computational and Functional Oncology An Hendrix Full professor, Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Ghent, Belgium Carlos Salomon Gallo Professor Julia V. Burnier Assistant Professor, McGill University NewsWork in progress OutputsWork in progress EventsWork in progress ISEV-ISAC-ISTH EV Flow Cytometry Intersociety Working GroupThe ISEV-ISAC-ISTH EV Flow Cytometry Intersociety Working Group, founded in 2015, is a collaboration between EV flow cytometry experts from ISEV, the International Society on Advancement of Cytometry (ISAC), and the International Society on Thrombosis and Haemostasis (ISTH). Together, these experts aim to improve the rigor and standardization of EV flow cytometry. To achieve this goal, they organize webinars, have produced a framework for transparent reporting that is supported by ISEV, ISAC and ISTH, and they have produced an educational compendium that provides extensive background information on the detection of EVs by flow cytometry. Output of the EV Flow Cytometry Working Group
Chair Contact InfoISEV-ISCT Intersociety Working GroupThe ISEV-ISCT Intersociety Working Group on Extracellular vesicles is a collaboration between ISEV and the International Society for Cell and Gene Therapy (ISCT). EVs secreted by stem cells constitute a novel therapeutic entity which offer great opportunities for therapy. Together, ISEV and ISCT collaborate and discuss standardization and regulatory aspects, co-organize sessions at respective annual meetings, and comment on the important developments in the field. All these activities help to foster the clinical applicability of EVs secreted by stem cells, and will facilitate the uptake of developed knowledge by the society. Output of the ISEV-ISCT Working Group
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